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6.3 Stratification: Pharmacogenetics and Drug Safety

Course description

Knowledge about drug action requires information about the involvement of polymorphic genes encoding e.g. drug metabolising enzymes, drug transporters, drug targets and human leukocyte antigens.

Pharmacogenetics is now an integrated part in drug development. Already today we know about specific genomic biomarkers that effectively predict ADRs and this development is expected to continue in the future.

The regulatory agencies now require pharmacogenomic aspects to be integrated into all different phases of drug development. Pharmacogenetic knowledge can also help to identify novel drug targets as well as to understand the bases for interindividual variation in drug response. IN addition, there are examples where drugs have been rescued based on novel pharmacogenetic information.

Course brochure

Course brochure (PDF-document)

Teachers Faculty

On-site course dates

August 27, 2012 - August 31, 2012

Course leader

Ingelman-Sundberg/Johansson/McHale

Location

Stockholm, Sweden

Application deadline

September 2, 2012

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